Tag: #miscarriage

Intralipid infusion therapy: boosting IVF success rates

Last modified: Dicembre 4, 2021

Intralipid infusion therapy is now used by many IVF specialists as a treatment for boosting IVF success rates, reducing the risk of miscarriage.

Nowadays, in vitro fertilisation (IVF) appears to be the most popular among fertility treatments. That is mainly due to its effectiveness and its relative simplicity as a medical procedure that couples can follow without changing much of their daily routine.

Intralipid infusion therapy

Intralipid infusion therapy is thought to protect the cell membranes

However, there are some couples who do not seem able to achieve pregnancy and deliver a healthy baby even though they have tried IVF several times. There might be several reasons underlying such IVF failures, including the age of the female and/or male partner, inherited genetic diseases, womb structure abnormalities, hormonal irregularities and, as seen quite often these past few years, immune system malfunction.

The latter, is based on the fact that a woman’s uterus might be hostile to receiving embryos transferred during the last step of the IVF treatment. There is evidence indicating that some cells of the immune system called natural killer cells (NK) could attack to the embryos recognizing them as foreign, causing them to fail implantation.

A quite promising therapy, called intralipid infusion therapy, could compromise the natural killer cells activity. In 2011, Dr George Ndukwe of the Care fertility clinic conducted a trial of the therapy on 50 women who have had several IVF failures. Approximately 50% of treated women got pregnant compared to 9% of women who got pregnant without receiving the intralipid infusion therapy. However, according to experts, a larger scale study is needed for confirming these data.

Intralipid infusion therapy is based on a blend of soya oil, egg yolk and glycerine and is thought to protect the cell membranes from the natural cell killers’ attacks. It is usually provided in tandem with IVF or IUI rather than as an alternative. It is a relatively low cost therapy, with no side effects that could increase success rates for women who have experienced implantation failures or early miscarriage/s.

Have you tried intralipid infusion therapy, or consider trying it in tandem with your IVF treatment?

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Low Dose Aspirin May Boost Female Fertility

Last modified: Novembre 6, 2015

Aspirin boosts female fertility, according to a new American study. Researchers from the National Institute of Child Health and Human Development in Maryland, USA discovered that aspirin at low doses can actually increase chances of pregnancy and live birth rate.

Low dose aspirin may boost female fertility

Low dose aspirin may boost female fertility according to researchers from USA

Today, Aspirin is one of the most commonly used drugs. In 2005, 43 million adults reported taking aspirin daily in USA, a number applying roughly to 1/5 of the population. Researchers highlight the fact that many doctors direct women who had previously experienced pregnancy loss and want to reconceive to take a low dose of aspirin. They, often, advise women to consider taking a small amount of aspirin daily (around 81 mg) in order to boost female fertility and increase their chances of having a baby. Fertility experts though comment that up to date scientific evidence is not sufficient for proving the method’s efficiency.

In contrast to the prevailing concept, scientists from the National Institute of Child Health and Human Development came to result that aspirin use does not prevent pregnancy loss. For the study, they recruited over a 1.000 of women with a history of miscarriage and randomly allocated them to take either aspirin or a placebo tablet. These women were followed for 6 months while they were trying to get pregnant. They reported no difference among the two study groups concerning pregnancy loss rates.

On the other hand, for women who had recently suffered a miscarriage the aspirin group exhibited increased pregnancy and live birth rates. According to the scientists’ initial publication in ‘’The Lanset’’, 78% of the aspirin group achieved pregnancy compared to 66% of the placebo tablet group.

In addition to these results, scientists analyzed inflammation levels of the women. They found that aspirin increased chances of conception by 17% and live birth rates by 20% in women with levels of inflammation, boosting female fertility.

During his speech at the American Society of Reproductive Medicine annual meeting where the study was presented, Professor Richard Paulson  advocated all women who want to get pregnant to take aspirin. ‘’it increases flow blood in the pelvis as well as endometrial thickness, there is no harm in women wanting to use aspirin for boosting fertility’’, says Professor Paulson.

Is that a good reason for considering aspirin use?

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