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Clinical Institute for Reproductive Medicine

Country / City
Pleven, Bulgaria
Pleven 5800, 20 Skobelev boulevard, Pleven, Bulgaria
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About the Clinic

Medical Center “Clinical Institute for Reproductive Medicine” Pleven was founded in 2007. The leading idea was to unite different specialists into one team, which primary purpose is to carry out complex diagnostics of reproductive failures.

Since its establishment in a small provincial town, MC CIRM Pleven is an innovator in the clinical practice on the implementation of immunoassays and therapy of infertility in Bulgaria. Algorithms originally created in MC CIRM Pleven been adopted and has been applied successfully in other reproductive centers and obstetricians in the country.

The team approach in the center is a precondition for the high success rate of IVF, our goal is not only the realization of pregnancy, but its storage and successful birth.

During all these years we keep the spirit and the mission of the center – to help, to love, to be empathetic. As a creator and manager of the center, I always knew that our success and sustainability of our hardships are due not only to the innovation and professionalism of our team. All our efforts are inspired and blessed by an idea and it will always stand above all. It is called – love for mankind.

Prof. Dr. Emiliana Konova, PhD

Why to choose our clinic?

We provide complex diagnostics and treatment of infertility.

Immunologycal testing:

  • Immune risk factors in reproductive failures;
  • Diagnosis of reproductive failure;
  • Evaluation of Recurrent Miscarriages;
  • Evaluation for Fetal Loss;
  • Prediction of Embryonic Loss;
  • Pregnancy monitoring.

Medical genetic consultations and tests;

Male factor infertility testing and treatment;

A wide range of diagnostic panels;

Personalized approach to each couple;

Consultations with various medical specialists – gynecologist, Immunologist, endocrinologist; Sperm and oocyte donation programs.

Our staff

Clinical Institute for Reproductive Medicine

Clinical Institute for Reproductive Medicine

Clinical Institute for Reproductive Medicine






Clinical Institute for Reproductive Medicine clinical Institute for Reproductive Medicine Clinical Institute for Reproductive Medicine






Our facilities


clinical Institute for Reproductive Medicine

Clinical Institute for Reproductive Medicine






Clinical Institute for Reproductive MedicineClinical Institute for Reproductive Medicine






Quality and accreditations

ISO 9001:2008 .

Quality Management System applicable to Prophylactics, diagnostics, treatment and all services for in vitro fertilization and immunological testing.

Languages spoken

Bulgarian, English, French, Macedonian, Serbian


  • IVF (In vitro fertilization)
  • ICSI (IntraCytoplasmic Sperm Injection)
  • IUI (Intra Uterine Insemination)
  • Sperm Aspiration (TESA)
  • Blastocyst Transfer
  • Testicular Biopsy (TESE)
  • Egg Freezing
  • Embryo Freezing
  • FET (Frozen Embryo Transfer)
  • Donor Eggs (Fresh)
  • Donor Sperm
  • Sperm Freezing

Egg Donation Program

Short description of the program:

The oocyte donor meets the following criteria:
1. Age – between 18 and 34 for unrelated donation; between 18 and 38 for related donation and persons under no judicial disability.
2. To be informed about the risks that she is subjected to.
3. To provide informed consent form, certified by a notary.
4. To be of good physical and mental health.
5. To have at least one live birth.

Commercialization of the egg donation is not permitted. It is only allowed to provide the donor a reasonable sum, which would compensate for travel expenses, temporary incapacity to work, pain, loss of time or daily income and other.

The potential donor is subjected to a whole range of gynecological, hormonal, serological and genetic examinations according to the Egg Donation Program in MC CIRM Pleven.
It is strictly forbidden to reveal the identity of the egg donor or any information which can lead to their identification by the recipients or third parties.

Legal status in country:
  • Donor anonymity
  • Donor Sperm
  • Frozen Eggs
  • Frozen Embryos
  • Max No embryos for transfer:
    Women under 38 years on day 3 max 3 embryos, on day 5 – max 2.
    Women over 38 years on day 3 max 4 embryos, on day 5 – max 3.

Waiting period for recipient: one year

Medications Included? Yes

Total costs for fresh cycle: 8000 BGN

What the costs include
  • Consultation
  • No of Visits: 4
  • Egg Donor medication
  • Pick up
  • ICSI
  • Blastocyst culture
  • Embryo transfer
Terms of payments

The payment is usually made at the date of the oocyte pick up.

Money back guarantee program:


Other details:

All of the oocytes retrieved from one donor are for one couple.

Additional Services:

  • Translation services
  • Parking
  • Public transport access

Success Rates

IVF/ICSI Clinical Pregnancy & Live Birth Rates (Fresh/Thaw Cycles)*
<35 35-37 38-40 41-42 >42
Fresh Cycles 48.1% / 45.19% 31.4% / 28.57% 19.6% / 19.6% 25.9% / 25.2% 14.3% / 14.3%
Frozen/Thaw cycles 25% / 20% 50% / 50%

A "clinical pregnancy" has a pregnancy sac seen in the uterus on ultrasound exam.
The "live birth rate" is the percentage of all IVF cycles that lead to a live birth. This rate does not include miscarriage or still birth and multiple-order births such as twins and triplets are counted as one pregnancy.

IVF/ICSI Clinical Pregnancy Rates (Egg Donation Cycles)
Fresh donor egg embryos Thawed donor egg embryos

Learn more aboutsuccess rates.


  • Consultations: 35 BGN
  • Ultrasounds during ovarian stimulation: 35 BGN
  • IVF (In vitro fertilization): 2700 BGN*
  • ICSI (IntraCytoplasmic Sperm Injection): 2900 BGN
  • IUI (Intra Uterine Insemination): 385 BGN
  • Blastocyst Transfer: 350 BGN
  • FET (Frozen Embryo Transfer): 430 BGN
  • Donor Eggs (Fresh): 900 BGN The medications used for the donor stimulation and all the expenses connected with the AR procedure (ultrasound, egg retrieval ivf/icsi fertilization and embryo transfer) are extra charged.
  • Donor Sperm: 600 BGN
  • Egg Freezing & Storage: 250 BGN storage 30 per month
  • Sperm Freezing & Storage: 150 BGN storage 30 per month
  • Embryo Freezing & Storage: 250 BGN storage 30 per month
  • Sperm Aspiration (TESA): 1300 BGN
  • Testicular Biopsy (TESE): 1300 BGN
  • Other Costs: * The price for IVF/ICSI includes: a. All ultrasounds and consultations with Gynecologist. b. Flow – day by day tests for Estradiol in stimulation procedure. c. Egg retrieval. d. Anesthesia. e. IVF/ICSI. In case of termination of the procedure during COHS, the patient should pay all ultrasounds and consultations with Gynecologist, that have been made
General Services
  • Translation services: 40 BGN per hour
Other Payment Information
  • Discounts
  • Payment plans
  • Credit cards

Short description of the fertility national law or policies in the country:

The national law and policies concerning the regulation of the assisted reproductive technologies corresponds to the European low and implement the following EC directives: 2004/23EO; 2006/17/EO; 2006/86/EO; 2012/39/EC.

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