Are the prospective reproductive outcomes in RPL couples related to sperm DNA fragmentation index (DFI) measured by SCSA, morphology and concentration at referral? Design A prospective cohort study including 95 couples seen between 01/04/2018 and 01/12/2019 at the tertiary Copenhagen RPL Unit, Copenhagen University Hospital, Rigshospitalet and Hvidovre Hospital, Denmark. The couples had experienced three […]
Many women undergoing IVF take supplements during treatment. The purpose of this review was to systematically review these nutritional supplements. The therapies studied are dehydroepiandrosterone (DHEA), melatonin, co-enzyme Q10 (CoQ1O), carnitine, selenium, vitamin D, myo-inositol, omega-3, Chinese herbs and dietary interventions. A literature search up to May 2023 was undertaken. The data suggest that a […]
Accurate prediction of fetal weight at birth is essential for effective perinatal care, particularly in the context of antenatal management, which involves determining the timing and mode of delivery. The current standard of care involves performing a prenatal ultrasound 24 hours prior to delivery. However, this task presents challenges as it requires acquiring high-quality images, […]
A team of researchers at the George Mason University College of Public Health as well as Northeastern University in the US have published research indicating a strong link between exposure to common pesticides and lower sperm counts. “Understanding how insecticides affect sperm concentration in humans is critical given their ubiquity in the environment and documented […]
US regulators will consider clinical trials of a system that mimics the womb, which could reduce deaths and disability for babies born extremely preterm. A hairless, pale-skinned lamb lies on its side in what appears to be an oversized sandwich bag filled with hazy fluid. Its eyes are closed, and its snout and limbs jerk […]
High childhood BMI is strongly associated with obesity and cardiometabolic disease and mortality in adulthood. Children conceived after FET have a higher risk of being born large for gestational age (LGA) than children conceived after NC. It is well-documented that being born LGA is associated with an increased risk of obesity in childhood, and it […]
The euploidy of embryos is unpredictable before transfer in in vitro fertilisation (IVF) treatments without pre-implantation genetic testing (PGT). Previous studies have suggested that morphokinetic characteristics using an artificial intelligence (AI)-based model in the time-lapse monitoring (TLM) system were correlated with the outcomes of frozen embryo transfer (FET), but the predictive effectiveness of the model […]
Infertility rates and the number of couples seeking fertility care have increased worldwide over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are being performed globally every year, but the success rate has remained at ~33%. Machine learning, an automated method of data analysis based on patterns and inference, is increasingly […]
This study was conducted to investigate the relationship of semen parameters in samples used for intracytoplasmic sperm injection (ICSI) with fertilization and pregnancy rates in infertile couples. Methods In this prospective study of Infertile couples with male factor infertility that had undergone ICSI, fractions of the same semen samples obtained for microinjection (to ensure the […]
In recent years, the amount of data produced in the field of ART has increased exponentially. The diversity of data is large, ranging from videos to tabular data. At the same time, artificial intelligence (AI) is progressively used in medical practice and may become a promising tool to improve success rates with ART. AI models […]
Since the late 1990s, the improved accessibility of biomedical data has hastened the application of artificial intelligence (AI) in reproductive medicine. AI can guide optimal clinical management for infertile couples, improving clinical and patient reported outcomes as well as promoting cost-effectiveness. Previously, AI for artificial reproduction has been applied to gamete selection and for predicting […]
An explosive increase in couples attending assisted reproductive technology has been recently observed, despite an overall success rate of about 20%–30%. Considering the assisted reproductive technology-related economic and psycho-social costs, the improvement of these percentages is extremely relevant. However, in the identification of predictive markers of assisted reproductive technology success, male parameters are largely underestimated […]
Fertility in women is dependent on ovarian follicles that contain immature oocytes. All follicles are formed during fetal development and should last for the reproductive lifespan of the woman. At most, there are a few million non-growing follicles in the ovaries of the female fetus during mid-gestation, and thereafter, the numbers decrease. At the onset […]
Researchers at the University of Kent have identified crucial new evidence on the safety and efficacy of a controversial area of IVF treatment – preimplantation genetic testing for aneuploidy (PGT-A). PGT-A is the screening for gross genetic (chromosomal) abnormalities in human IVF embryos with a view to improving IVF success rates and guarding against miscarriage. […]
Endometriosis is an estrogen-dependent chronic gynecologic disorder that significantly reduces the quality of life of affected women. Characterized by adhesions of endometrial fragments in extra-uterine sites (predominantly in the peritoneal cavity and ovary but occasionally on the diaphragm, liver, and abdominal wall), the condition occurs in ~10% of the general population and is associated with […]
Sperm cells moving their long tail to swim through the body in search of an egg is a familiar image, but a fully ‘powered’ tail may not be the key to success, according to a new UK study which could be crucial for improving the outcomes of assisted fertility treatments. Propulsion of sperm and how […]
In human populations, there are strong seasonal patterns of births that vary across geographic regions and time periods. However, previous studies of seasonality and fecundity are limited because they examine season of birth rather than season of conception and therefore neglect to account for seasonal variation in initiating attempts to conceive or pregnancy loss or […]
Dangerous levels of microwave radiation from Wi-Fi and other devices were discovered in school classrooms in Ontario as measured by students from Peel District School Board. The radiation levels found were strong enough to cause infertility problems. The students organized an open meeting in order to inform all school students about the dangers they are […]
Does male age affect embryo growth or quality in couples undergoing IVF treatment? Literature shows that Advanced paternal age (APA) is associated with decreased sperm quality and fecundity. However, the effect of male age on embryo growth in an IVF setting remains inconclusive. Literature concerning male influences on IVF success is scarce and approaches used […]
To explore the possible influence of sperm quality, as assessed by prewash total sperm count (TSC), on cumulative success rates in assisted reproduction cycles. Methods: Retrospective study carried out in private IVF centre. Seven hundred sixty-five couples undergoing complete ICSI cycles, i.e. whose all embryos were transferred or disposed of. Couples were characterised by male […]
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